The Effect of Chronic Candesartan Therapy on the Metabolic Profile and Renal Tissue Cytokine Levels in the Obese Zucker Rat

THE EFFECT OF 12 WEEKS OF MODERATE INTENSITY CONTINUOUS TRAINING (MICT) ON INFLAMMATORY AND ANGIOGENESIS FACTORS OF VISCERAL AND SUBCUTANEOUS ADIPOSE TISSUE IN OBESE RATS: A SEMI-EXPERIMENTAL STUDY

Background & Aims: Physical activity by modulating angiogenesis in adipose tissue, effects on the entire body metabolic profile. Therefore, the aim of this study was to investigate the effect of 12 weeks of moderate intensity continuous training on VEGF, PEDF and PAI-1 of visceral and subcutaneous adipose tissue in obese rats. Materials & Methods: 15 male Wistar rats were divided into 2 groups...

The intraction effect of ten week combined exercise training (resistance-aerobic) and mix supplemantation (L-carnitine-caffein-arginine) on adiponectin, leptin and lipid profile in obese men

Introduction and purpose: the effect of resistance and aerobic exercise on improving the metabolic conditions of obese people has been confirmed; But the question of whether consuming energy supplements along with exercise improves the metabolic status and blood lipid profile of individuals is a new approach that has been considered. The aim of this investigation was to study the interactive ef...

The Effect of Continuous Training on Betatrophin Levels and Lipid Profile in Obese Men

Background and Aim: Many epidemiologic studies have shown alterations in the concentration of betatrophin (ANGPTL8) in metabolic diseases such as diabetes, obesity and metabolic syndrome. The purpose of this study was to evaluate the effect of 8 weeks of continuous exercise on serum betatrophin and lipid levels in obese men. Methods: In this study, 20 obese men were randomly divided into contro...

The effect of eight weeks combined exercise training (resistance-endurance) and omega-3 ingestion on the levels of fetuin-A and metabolic profile in obese elderly women

Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat.

The obese Zucker rat reportedly has increased activity of the intrarenal renin-angiotensin-aldosterone system, which conceptually could contribute to elevated salt sensitivity and blood pressure (BP). Our aim was to determine whether there was increased angiotensin II type 1 receptor (AT(1)R)-mediated upregulation of expression or activity of the bumetanide-sensitive Na-K-2Cl cotransporter, the...